Goodpasture Syndrome ICD 10 Explained: A Complete Guide for Medical Coders

Goodpasture Syndrome ICD 10

Goodpasture syndrome (GPS) is a rare autoimmune disease that affects the lungs and kidneys. It is caused by antibodies that attack the basement membrane, a thin layer of tissue that separates the blood vessels from the organs. The basement membrane is found in many parts of the body, but GPS mainly targets the glomerular basement membrane (GBM) in the kidneys and the alveolar basement membrane (ABM) in the lungs.

The ICD-10 code for Goodpasture syndrome is M31.0. This code falls under the category of “Other diseases of kidney and ureter”, specifically “Other specified diseases of kidney and ureter”. The ICD-10 is a system of codes that classify diseases and health problems for statistical and clinical purposes. It is maintained by the World Health Organization (WHO) and updated periodically.

Signs and Symptoms of Goodpasture Syndrome

The symptoms of GPS vary depending on the severity and extent of the damage to the lungs and kidneys. Some common signs and symptoms include:

  • Coughing up blood
  • Shortness of breath
  • Chest pain
  • Blood in the urine
  • Protein in the urine
  • Swelling of the limbs or face
  • High blood pressure
  • Fatigue
  • Fever
  • Joint pain
  • Weight loss

Diagnosis of Goodpastur Syndrome

The diagnosis of GPS is based on the presence of anti-GBM antibodies in the blood or tissue samples, as well as the clinical features and the results of imaging tests such as chest X-ray, kidney ultrasound, or CT scan. A kidney or lung biopsy may be needed to confirm the diagnosis and assess the degree of inflammation and scarring.


The treatment of GPS aims to stop the production of anti-GBM antibodies and prevent further damage to the lungs and kidneys. The main treatment options are:

  • Immunosuppressive drugs: These medications suppress the immune system and reduce inflammation and antibody levels. Examples include corticosteroids, cyclophosphamide, rituximab, and azathioprine.
  • Plasmapheresis: This is a procedure that removes the plasma, the liquid part of the blood, and replaces it with fresh plasma or a plasma substitute. This helps to remove the anti-GBM antibodies and other harmful substances from the blood.
  • Dialysis: This is a process that filters the blood and removes the waste products and excess fluid that accumulate due to kidney failure. It can be done either by using a machine (hemodialysis) or the lining of the abdomen (peritoneal dialysis).
  • Kidney transplant: This is a surgery that replaces a damaged kidney with a healthy one from a donor. It is usually considered a last resort when the kidney function is very low and dialysis is not effective or tolerable.

The prognosis of GPS depends on several factors, such as the age, the onset, the severity, the response to treatment, and the presence of complications. The mortality rate of GPS has decreased significantly over the years, thanks to the advances in diagnosis and treatment. However, some patients may still develop chronic kidney disease, end-stage renal disease, or pulmonary fibrosis, which can affect their quality of life and life expectancy.

GPS is a rare but serious condition that requires prompt diagnosis and treatment. If you or someone you know has any of the symptoms mentioned above, please consult a doctor as soon as possible. Early intervention can make a difference in the outcome and the recovery of GPS.


(1) Goodpasture syndrome – Wikipedia.
(2) ICD10 code of Goodpasture syndrome and ICD9 code
(3) ahesia.
(4) Goodpasture syndrome – OrphanAnesthesia.

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Goodpasture Syndrome ICD 10 Explained: A Complete Guide for Medical Coders
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